Formulated collagen gel “…causes a large and rapid time-dependent effect on tissue growth rates.” A single application “increases the healing rate of neuropathic DFUs...”, and more frequent applications “…hold promise to significantly improve overall incidence of complete wound closure.
Three patients with wounds of at least 18 months to 3 years duration, and well-documented prior therapies (including NPWT) were studied. All three patients responded favorably to a treatment regimen of weekly debridement (if needed) and weekly application of type I formulated collagen gel”… “Two of the three patients achieved complete wound closure in 4-5 weeks. The third patient, with the largest wound (78 cm3…) achieved 100% granulation and a 59% reduction in wound volume after 6 weeks”…. Study nurses reported that “…weekly use of type I formulated collagen gel required less time and was more compatible with their busy schedules than standard care of daily (or multiple times daily) dressing changes.
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