Excellagen is a highly-purified formulated fibrillar bovine Type I collagen-based topical gel (2.6%) for wound care management. Excellagen's sterile, physiologic formulation provides protein stabilization and maintenance of Excellagen's key structural and functional properties and allows for easy topical application. The FDA-cleared professional use Excellagen sterile formulation comes in ready-to-use, pre-filled, single-use syringes.
It is recommended that Excellagen be applied during debridement in the presence of blood cells and platelets, which are involved with the release of endogenous growth factors.1 Excellagen has been shown to activate human platelets, triggering the release of platelet-derived growth factor (PDGF). 2 Collagen is considered an important and essential protein that supports a favorable wound healing environment.
Excellagen may be used by healthcare professionals for the management of diabetic ulcers and other dermal wounds including partial and full-thickness wounds, pressure ulcers, venous ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (donor sites/graft, post-Moh's surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, second-degree burns and skin tears) and draining wounds.
Yes, Excellagen is labeled for use by health care professionals only.
We believe it is important for you to get involved with your treatment and to become part of the solution. If you have chronic diabetic foot ulcers and have become frustrated with the discomfort and lifestyle changes due to this condition, click here to download information to bring to your physician during your next visit.
Since Excellagen is new and just recently received FDA clearance, your health insurer may not yet provide reimbursement but ask your healthcare provider or insurer.
Excellagen is intended for topical application following debridement (with weekly outer dressing changes). Because Excellagen is biodegradable and biocompatible there is no need for daily dressing changes.
Debridement is the surgical removal of dead tissue and debris that exposes the viable wound bed and healing edges of the wound and results in an influx of blood into the wound. It plays an important role in activating and facilitating wound healing, and is part of good standardized wound care.
Excellagen will initially be supplied in the form of a kit consisting of four single-use 1.0 cc syringes, each containing 0.5 cc of Excellagen gel, and four sterile flexible applicators to facilitate topical administration to the wound site over a course of up to four treatments.
When treating a wound, it is very important to take pressure off the affected area. This can be accomplished with specialized footwear or casts provided in consultation with your healthcare provider.
No. Active wound infections should be treated and resolved prior to using Excellagen.
Excellagen should not be used in individuals with a known sensitivity to bovine collagen. Detailed information about contraindications can be found in the Directions for Use.